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Article

A signal transduction protein cues proteolytic events critical to Caulobacter cell cycle progression.

Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 2002

Hung Dean Y, Shapiro Lucy

Abstract excerpt

Temporally controlled proteolysis of the essential response regulator, CtrA, is critical for cell cycle progression in Caulobacter crescentus. CtrA binds to and silences the origin of replication in swarmer cells. The initiation of replication depends on the proteolysis of CtrA. We present evidence that DivK, an essential single-domain response regulator, contributes to the control of the G(1)-S transition by...

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Identifiers

PMID: 12237413
DOI: 10.1073/pnas.202495099
PMCID: PMC130603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A signal transduction protein cues proteolytic events critical to Caulobacter cell cycle progression.PMID 12237413Read ↗

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