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Article

The interaction between ETS transcription factor family members and microRNAs: A novel approach to cancer therapy

5 May 2022

Abstract excerpt

In cancer biology, ETS transcription factors promote tumorigenesis by mediating transcriptional regulation of numerous genes via the conserved ETS DNA-binding domain. MicroRNAs (miRNAs) act as posttranscriptional regulators to regulate various tumor-promoting or tumor-suppressing factors. Interactions between ETS factors and miRNAs regulate complex tumor-promoting and tumor-suppressing networks. This review...

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PMID: 35658214
DOI: 10.1016/j.biopha.2022.113069

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