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Article

Association of Genetic Polymorphisms in MicroRNAs With Type 2 Diabetes Mellitus in a Chinese Population.

Frontiers in endocrinology - 1 Jan 2020

Zhu Zaihan, Zhang Yanfen, Bai Ruocen, Yang Ru, Shan Zhongyan, Ma Chunyan, Yang Jun, Sun Dandan

Abstract excerpt

Introduction: MicroRNAs (miRNA) involved in the insulin signaling pathways deeply affect the pathogenesis of T2DM. The aim of this study was to assess the association between single nucleotide polymorphisms (SNP) of the related miRNAs (let-7f rs10877887, let-7a-1 rs13293512, miR-133a-1 rs8089787, miR-133a-2 rs13040413, and miR-27a rs895819) and susceptibility to type 2 diabetes mellitus (T2DM), and its possible...

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Identifiers

PMID: 33628196
DOI: 10.3389/fendo.2020.587561
PMCID: PMC7897684

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