Article
Type 2 diabetes and cardiometabolic risk may be associated with increase in DNA methylation of FKBP5
19 Jun 2018
Abstract excerpt
Subclinical hypercortisolism and hypothalamic-pituitary-adrenal (HPA) axis dysfunction are associated with type 2 diabetes (T2DM), cardiovascular disease, and metabolic dysfunction. Intronic methylation of FKBP5 has been implicated as a potential indicator of chronic cortisol exposure. Our overall objective in this study was to determine the association of chronic cortisol exposure, measured via percent...
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