A pilot investigation of genetic and epigenetic variation of FKBP5 and response to exercise intervention in African women with obesity.

doi:10.1038/s41598-022-15678-6

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A pilot investigation of genetic and epigenetic variation of FKBP5 and response to exercise intervention in African women with obesity.

Scientific reports - 11 Jul 2022

Willmer Tarryn, Oosthuizen Amberly, Dias Stephanie, Mendham Amy E, Goedecke Julia H, Pheiffer Carmen

Abstract excerpt

We investigated gluteal (GSAT) and abdominal subcutaneous adipose tissue (ASAT) DNA methylation of FKBP5 in response to a 12-week intervention in African women with obesity, as well as the effect of the rs1360780 single nucleotide polymorphism (SNP) on FKBP5 methylation, gene expression and post-exercise training adaptations in obesity and metabolic related parameters. Exercise (n = 19) participants underwent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exercise

Share to Genotype

Share to Obesity

Share to Pilot Projects

Share to Polymorphism, Single Nucleotide

Share to Resistance Training

Share to Tacrolimus Binding Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 35817784
DOI: 10.1038/s41598-022-15678-6
PMCID: PMC9273786

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A pilot investigation of genetic and epigenetic variation of FKBP5 and response to exercise intervention in African women with obesity.PMID 35817784Read ↗

DNA methylation of FKBP5 in South African women: associations with obesity and insulin resistanceSemantic proximity Read ↗

Changes in subcutaneous adipose tissue microRNA expression in response to exercise training in African women with obesitySemantic proximity Read ↗

Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated lociSemantic proximity Read ↗

Distinct abdominal and gluteal adipose tissue transcriptome signatures are altered by exercise training in African women with obesitySemantic proximity Read ↗

Methylome-Wide Association Study of Central Adiposity Implicates Genes Involved in Immune and Endocrine SystemsSemantic proximity Read ↗

The impact of exercise interventions and omega-3 polyunsaturated fatty acid supplementation on DNA methylation and gene expressionSemantic proximity Read ↗

Exercise: putting action into our epigenome.Semantic proximity Read ↗

African genetic ancestry interacts with body mass index to modify risk for uterine fibroids.Semantic proximity Read ↗

8-week Combined Exercise Protocol Promote Health and Cardiovascular Benefits in Obese Women by Epigenetic Modifications: a Prospective StudySemantic proximity Read ↗

Type 2 diabetes and cardiometabolic risk may be associated with increase in DNA methylation of FKBP5Semantic proximity Read ↗

An analysis of DNA methylation in human adipose tissue reveals differential modification of obesity genes before and after gastric bypass and weight lossSemantic proximity Read ↗

CPT1A methylation is associated with plasma adiponectin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.