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Article

Alternative Method to Detect Neuronal Degeneration and Amyloid β Accumulation in Free-Floating Brain Sections With Fluoro-Jade.

ASN neuro - 1 Jan 2000

Gutiérrez Irene L, González-Prieto Marta, García-Bueno Borja, Caso Javier R, Leza Juan C, Madrigal José L M

Abstract excerpt

Fluoro-Jade is a fluorescein-derived fluorochrome which specifically binds to damaged neurons. Due to this characteristic, it is commonly used for the histochemical detection and quantification of neurodegeneration in mounted brain sections. Here, we describe an alternative and simpler histochemistry protocol based on the use of free-floating brain sections. For this purpose, we have used brain slices from...

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Identifiers

PMID: 29950099
DOI: 10.1177/1759091418784357
PMCID: PMC6043921

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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