Article
Neuroanatomical phenotyping of the mouse brain with three-dimensional autofluorescence imaging.
Physiological genomics - 1 Aug 2012
Gleave Jacqueline A, Wong Michael D, Dazai Jun, Altaf Maliha, Henkelman R Mark, Lerch Jason P, Nieman Brian J
Abstract excerpt
The structural organization of the brain is important for normal brain function and is critical to understand in order to evaluate changes that occur during disease processes. Three-dimensional (3D) imaging of the mouse brain is necessary to appreciate the spatial context of structures within the brain. In addition, the small scale of many brain structures necessitates resolution at the ∼10 μm scale. 3D optical...
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