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Article

ZNF281 inhibits neuronal differentiation and is a prognostic marker for neuroblastoma

25 Jun 2018

Abstract excerpt

Derangement of cellular differentiation because of mutation or inappropriate expression of specific genes is a common feature in tumors. Here, we show that the expression of ZNF281, a zinc finger factor involved in several cellular processes, decreases during terminal differentiation of murine cortical neurons and in retinoic acid-induced differentiation of neuroblastoma (NB) cells. The ectopic expression of...

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PMID: 29941555
DOI: 10.1073/pnas.1801435115

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