Article
Molecular characterization of hepatitis B virus (HBV) in African children living in Australia identifies genotypes and variants associated with poor clinical outcome.
The Journal of general virology - 1 Aug 2018
Bannister Elizabeth G, Yuen Lilly, Littlejohn Margaret, Edwards Rosalind, Sozzi Vitina, Colledge Danni, Li Xin, Locarnini Stephen, Hardikar Winita, Revill Peter A
Abstract excerpt
Migration from sub-Saharan Africa is contributing to the rising incidence of chronic hepatitis B (CHB) infection and its complications in Australia. African CHB is associated with unique genotypes, such as E and A1, which are associated with reduced vaccine efficacy and early-onset hepatocellular carcinoma, respectively, although the prevalence of these genotypes outside Africa is poorly described....
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