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Article

Mapping hepatitis B virus genotypes on the African continent from 1997 to 2021: a systematic review with meta-analysis.

Scientific reports - 7 Apr 2023

Kafeero Hussein Mukasa, Ndagire Dorothy, Ocama Ponsiano, Kato Charles Drago, Wampande Eddie, Walusansa Abdul, Kajumbula Henry, Kateete David, Ssenku Jamilu E, Sendagire Hakim

Abstract excerpt

Hepatitis B virus (HBV) has ten genotypes (A-J) and over 40 sub-genotypes based on the divergence of ≥ 8% and 4 to < 8% in the complete genome respectively. These genotypes and sub-genotypes influence the disease prognosis, response to therapy and route of viral transmission. Besides, infection with mixed genotypes and recombinant genotypes has also been reported. This study aimed at mapping the de novo genotypes...

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Identifiers

PMID: 37029173
DOI: 10.1038/s41598-023-32865-1
PMCID: PMC10082212

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