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Article

Molecular characteristics and clinical relevance of African genotypes and subgenotypes of hepatitis B virus.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde - 8 Aug 2018

Kramvis A

Abstract excerpt

Hepatitis B virus (HBV), a DNA virus, replicates via an RNA intermediate, through reverse transcription catalysed by the viral polymerase that lacks proof reading ability. Thus sequence heterogeneity is a feature of HBV being classified into at least 9 genotypes and over 35 subgenotypes. Africa has a high diversity of genotypes/subgenotypes, with distinct geographical distributions. Genotype A is found mainly in...

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Identifiers

PMID: 30182908
DOI: 10.7196/SAMJ.2018.v108i8b.13495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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