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Bringing Culture to the Uncultured: Coxiella burnetii and Lessons for Obligate Intracellular Bacterial Pathogens

5 Sept 2013

Abstract excerpt

Human diseases caused by obligate intracellular bacterial pathogens result in significant morbidity and mortality. Obligate intracellular bacteria that replicate in the cytoplasm of host endothelial cells include Rickettsia prowazekii, Rickettsia rickettsii, and Orientia tsutsugamushi (etiologic agents of epidemic typhus, Rocky Mountain spotted fever, and scrub typhus, respectively). Residing in specialized...

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PMID: 24039571
DOI: 10.1371/journal.ppat.1003540

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