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[Reproduction,genotype identification and evaluation of APP/PS1 transgenic mice].

Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology - 8 Feb 2018

Tan Long, Li Hai-Qiang, Li Yi-Bo, Liu Wei, Pang Wei, Jiang Yu-Gang

Abstract excerpt

OBJECTIVES: To identify the genotype of (APP/PS1) transgenic mice and evaluate the changing of cognitive and behavioral fu nctions, provide an effective animal model for the Alzheimer's disease (AD) research. METHODS: Male APP/PS1 transgenic mice mated with female APP/PS1 transgenic mice, and the genotype of their filial mice was identified by PCR. The APP +/PS1 + mice were assigned into AD model group (AD group,...

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Identifiers

PMID: 29926672
DOI: 10.12047/j.cjap.5541.2018.027

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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