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Fetal sex determination using circulating cell‐free fetal DNA (ccffDNA) at 11 to 13 weeks of gestation

18 Aug 2010

Abstract excerpt

OBJECTIVE: To examine the performance of a mass spectrometry-based detection platform using three Y-chromosome sequences for fetal sex determination from circulating cell-free fetal DNA (ccffDNA) in maternal blood in the first trimester of pregnancy. METHODS: We extracted ccffDNA for the determination of fetal sex from stored maternal plasma obtained at 11 to 13 weeks' gestation from singleton pregnancies with...

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PMID: 20721878
DOI: 10.1002/pd.2582

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