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The Importance of Podocyte Adhesion for a Healthy Glomerulus

14 Oct 2014

Abstract excerpt

Podocytes are specialized epithelial cells that cover the outer surfaces of glomerular capillaries. Unique cell junctions, known as slit diaphragms, which feature nephrin and Neph family proteins in addition to components of adherens, tight, and gap junctions, connect adjacent podocyte foot processes. Single gene disorders affecting the slit diaphragm result in nephrotic syndrome in humans, characterized by...

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PMID: 25352829
DOI: 10.3389/fendo.2014.00160

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