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Article

Short-Form Bomanins Mediate Humoral Immunity in Drosophila.

Journal of innate immunity - 1 Jan 2018

Lindsay Scott A, Lin Samuel J H, Wasserman Steven A

Abstract excerpt

The Bomanins (Boms) are a family of a dozen secreted peptides that mediate the innate immune response governed by the Drosophila Toll receptor. We recently showed that deleting a cluster of 10 Bom genes blocks Toll-mediated defenses against a range of fungi and gram-positive bacteria. Here, we characterize the activity of individual Bom family members. We provide evidence that the Boms overlap in function and...

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Identifiers

PMID: 29920489
DOI: 10.1159/000489831
PMCID: PMC6158068

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