Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oxytocin receptor gene variations and socio-emotional effects of MDMA: A pooled analysis of controlled studies in healthy subjects.

PloS one - 1 Jan 2018

Vizeli Patrick, Liechti Matthias E

Abstract excerpt

Methylenedioxymethamphetamine (MDMA) increases oxytocin, empathy, and prosociality. Oxytocin plays a critical role in emotion processing and social behavior and has been shown to mediate the prosocial effects of MDMA in animals. Genetic variants, such as single-nucleotide polymorphisms (SNPs), of the oxytocin receptor (OXTR) may influence the emotional and social effects of MDMA in humans. The effects of common...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Alleles
Share to Empathy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Oxytocin

Share to Polymorphism, Single Nucleotide

Share to Receptors, Oxytocin

Share to Social Behavior

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 29912955
DOI: 10.1371/journal.pone.0199384
PMCID: PMC6005537

Genes

OXTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oxytocin receptor gene variations and socio-emotional effects of MDMA: A pooled analysis of controlled studies in healthy subjects.PMID 29912955Read ↗

Oxytocin receptor gene variation predicts subjective responses to MDMA.Semantic proximity Read ↗

Revisiting the impact of OXTR rs53576 on empathy: A population-based study and a meta-analysis.Semantic proximity Read ↗

A Systematic Review of MDMA’s Effects on Social Functioning in Placebo-Controlled TrialsSemantic proximity Read ↗

Oxytocin receptor genetic variation relates to empathy and stress reactivity in humans.Semantic proximity Read ↗

The influence of rs53576 polymorphism in the oxytocin receptor (OXTR) gene on empathy in healthy adults by subtype and ethnicity: a systematic review and meta-analysis.Semantic proximity Read ↗

The Association of Oxytocin Receptor Gene (OXTR) Polymorphisms with Antisocial Behavior: A Meta-analysis.Semantic proximity Read ↗

Association between oxytocin receptor gene polymorphisms and self-rated 'empathic concern' in schizophrenia.Semantic proximity Read ↗

Randomized clinical trial shows no substantial modulation of empathy-related neural activation by intranasal oxytocin in autism.Semantic proximity Read ↗

A common oxytocin receptor gene (OXTR) polymorphism modulates intranasal oxytocin effects on the neural response to social cooperation in humans.Semantic proximity Read ↗

The oxytocinergic system modulates sadistic context-dependent empathy in humans.Semantic proximity Read ↗

Oxytocin receptor gene rs53576 polymorphism modulates oxytocin-dopamine interaction and neuroticism traits--a SPECT study.Semantic proximity Read ↗

Oxytocin-related single-nucleotide polymorphisms, family environment, and psychopathic traits.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.