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Article

Oxytocin receptor gene variation predicts subjective responses to MDMA.

Social neuroscience - 1 Dec 2016

Bershad Anya K, Weafer Jessica J, Kirkpatrick Matthew G, Wardle Margaret C, Miller Melissa A, de Wit Harriet

Abstract excerpt

3,4-Methylenedioxymethamphetamine (MDMA, "ecstasy") enhances desire to socialize and feelings of empathy, which are thought to be related to increased oxytocin levels. Thus, variation in the oxytocin receptor gene (OXTR) may influence responses to the drug. Here, we examined the influence of a single OXTR nucleotide polymorphism (SNP) on responses to MDMA in humans. Based on findings that carriers of the A allele...

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Source

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Identifiers

PMID: 26787430
DOI: 10.1080/17470919.2016.1143026
PMCID: PMC4988944

Genes

OXTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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