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Article

Oxytocin receptor gene rs53576 polymorphism modulates oxytocin-dopamine interaction and neuroticism traits--a SPECT study.

Psychoneuroendocrinology - 1 Sept 2014

Chang Wei Hung, Lee I Hui, Chen Kao Chin, Chi Mei Hung, Chiu Nan-Tsing, Yao Wei Jen, Lu Ru-Band, Yang Yen Kuang, Chen Po See

Abstract excerpt

Brain oxytocin and dopamine systems interact to modulate social cognitive behavior. Whether the interactions are modulated by oxytocin receptor (OXTR) gene variations remains unclear. Considering the dopamine transporter (DAT) availability as an endophenotype and the degree of dopamine-mediated neuroticism as a phenotype of the OXTR genotypes, the current molecular imaging study used [(99m)Tc]TRODAT-1 single...

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Source

Identifiers

PMID: 25001970
DOI: 10.1016/j.psyneuen.2014.05.020

Genes

OXTR
MPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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