Article
Phenotypic Convergence: Distinct Transcription Factors Regulate Common Terminal Features.
Cell - 26 Jul 2018
Konstantinides Nikolaos, Kapuralin Katarina, Fadil Chaimaa, Barboza Luendreo, Satija Rahul, Desplan Claude
Abstract excerpt
Transcription factors regulate the molecular, morphological, and physiological characteristics of neurons and generate their impressive cell-type diversity. To gain insight into the general principles that govern how transcription factors regulate cell-type diversity, we used large-scale single-cell RNA sequencing to characterize the extensive cellular diversity in the Drosophila optic lobes. We sequenced 55,000...
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