Article
Host genetics and microbiome associations through the lens of genome wide association studies.
Current opinion in microbiology - 1 Aug 2018
Weissbrod Omer, Rothschild Daphna, Barkan Elad, Segal Eran
Abstract excerpt
Recent studies indicate that the gut microbiome is partially heritable, motivating the need to investigate microbiome-host genome associations via microbial genome-wide association studies (mGWAS). Existing mGWAS demonstrate that microbiome-host genotype associations are typically weak and are spread across multiple variants, similar to associations often observed in genome-wide association studies (GWAS) of...
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