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Article

NLRP3 in somatic non-immune cells of rodent and primate testes

15 Jun 2018

Abstract excerpt

Abstract NLRP3 is part of the NLRP3 inflammasome and a global sensor of cellular damage. It was recently discovered in rodent Sertoli cells. We investigated NLRP3 in mouse, human and non-human primate (marmoset and rhesus macaque) testes, employing immunohistochemistry. Sertoli cells of all species expressed NLRP3, and the expression preceded puberty. In addition, peritubular cells of the adult human testes...

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PMID: 29907661
DOI: 10.1530/rep-18-0111

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