Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influence of pH on the uptake and toxicity of β-blockers in embryos of zebrafish, Danio rerio.

Aquatic toxicology (Amsterdam, Netherlands) - 1 Aug 2018

Bittner Lisa, Teixido Elisabet, Seiwert Bettina, Escher Beate I, Klüver Nils

Abstract excerpt

ß-Blockers are weak bases with acidity constants related to their secondary amine group. At environmental pH they are protonated with the tendency to shift to their neutral species at more alkaline pH. Here we studied the influence of pH from 5.5 to 8.6 on the toxicity of the four ß-blockers atenolol, metoprolol, labetalol and propranolol in zebrafish embryos, relating toxicity not only in a conventional way to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenergic beta-Antagonists
Share to Embryo, Nonmammalian

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Rate

Share to Metoprolol

Share to Propranolol

Share to Toxicity Tests

Share to Water Pollutants, Chemical

Share to Zebrafish

Source

Identifiers

PMID: 29906695
DOI: 10.1016/j.aquatox.2018.05.020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of pH on the uptake and toxicity of β-blockers in embryos of zebrafish, Danio rerio.PMID 29906695Read ↗

The Acute Toxicity and Cardiotoxic Effects of Levofloxacin on Zebrafish (Danio rerio)Semantic proximity Read ↗

Multi-phenotypic and bi-directional behavioral screening of zebrafish larvae.Semantic proximity Read ↗

Teratological Effects of a Panel of Sixty Water-Soluble Toxicants on Zebrafish DevelopmentSemantic proximity Read ↗

Drugs That Induce Repolarization Abnormalities Cause Bradycardia in ZebrafishSemantic proximity Read ↗

Metformin and guanylurea reduce survival, but have limited sublethal effects in larval zebrafish ( <i>Danio rerio</i> )Semantic proximity Read ↗

Effects of 4 testing arena sizes and 11 types of embryo media on sensorimotor behaviors in wild-type and <i>chd7</i> mutant zebrafish larvaeSemantic proximity Read ↗

Automated high-throughput heart rate measurement in medaka and zebrafish embryos under physiological conditionsSemantic proximity Read ↗

Visual–Acoustic Thigmotaxis in Zebrafish Larvae: A High throughput NAM for Neurotoxicity AssessmentSemantic proximity Read ↗

Zebrafish as a model organism in One Health Toxicology: Impact of solvents and exposure routes on the toxicity of platinum anticancer drugsSemantic proximity Read ↗

Benoxacor caused developmental and cardiac toxicity in zebrafish larvaeSemantic proximity Read ↗

Embryonic exposure to diclofenac disturbs actin organization and leads to myofibril misalignment.Semantic proximity Read ↗

Isovaleric, methylmalonic, and propionic acid decrease anesthetic EC50 in tadpoles, modulate glycine receptor function, and interact with the lipid 1,2-dipalmitoyl-Sn-glycero-3-phosphocholine.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.