Article

Metformin and guanylurea reduce survival, but have limited sublethal effects in larval zebrafish ( <i>Danio rerio</i> )

2023-12-04

Abstract excerpt

Metformin is the most common first-line oral therapeutic agent used in the treatment of type-2 diabetes, one of the most prevalent chronic diseases in North America. Post excretion, the compound enters wastewater treatment plants where it is partially bio-transformed by bacteria into guanylurea. Both metformin and guanylurea enter freshwater environments in wastewater effluent where they are available for uptake b...

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Literature Corpus work: eb11f968-0c96-5f16-b220-31465b4bad1a
DOI: 10.1101/2023.12.01.569578

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