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Article

Influenza A virus-derived siRNAs increase in the absence of NS1 yet fail to inhibit virus replication.

RNA (New York, N.Y.) - 1 Sept 2018

Tsai Kevin, Courtney David G, Kennedy Edward M, Cullen Bryan R

Abstract excerpt

While the issue of whether RNA interference (RNAi) ever forms part of the antiviral innate immune response in mammalian somatic cells remains controversial, there is considerable evidence demonstrating that few, if any, viral small interfering RNAs (siRNAs) are produced in infected cells. Moreover, inhibition of RNAi by mutational inactivation of key RNAi factors, such as Dicer or Argonaute 2, fails to enhance...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29903832
DOI: 10.1261/rna.066332.118
PMCID: PMC6097656

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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