Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association mapping from sequencing reads using k-mers.

eLife - 13 Jun 2018

Rahman Atif, Hallgrímsdóttir Ingileif, Eisen Michael, Pachter Lior

Abstract excerpt

Genome wide association studies (GWAS) rely on microarrays, or more recently mapping of sequencing reads, to genotype individuals. The reliance on prior sequencing of a reference genome limits the scope of association studies, and also precludes mapping associations outside of the reference. We present an alignment free method for association studies of categorical phenotypes based on counting [Formula: see...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Ampicillin
Share to Ampicillin Resistance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Anti-Bacterial Agents

Share to Genetic Loci

Share to Genome

Share to Software

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 29897334
DOI: 10.7554/eLife.32920
PMCID: PMC6044908

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association mapping from sequencing reads using k-mers.PMID 29897334Read ↗

Efficient association mapping from k-mers-An application in finding sex-specific sequences.Semantic proximity Read ↗

Association Mapping from Sequencing Reads Using <i>K</i> -mersSemantic proximity Read ↗

Reduced ambiguity and improved interpretability of bacterial genome-wide associations using gene-cluster-centric k-mers.Semantic proximity Read ↗

Sequence element enrichment analysis to determine the genetic basis of bacterial phenotypesSemantic proximity Read ↗

Taxonomic-free metagenome GWAS to identify gut microbiome functions influencing host phenotypesSemantic proximity Read ↗

Sequence element enrichment analysis to determine the genetic basis of bacterial phenotypesSemantic proximity Read ↗

MoleMap: fast alignment-free molecule mapping for long-read and linked-read sequencing dataSemantic proximity Read ↗

Single nucleotide polymorphism libraries: why and how are we building them?Semantic proximity Read ↗

Genome-wide association mapping in bacteria?Semantic proximity Read ↗

Toward fast and accurate SNP genotyping from whole genome sequencing data for bedside diagnosticsSemantic proximity Read ↗

Effects of spaced k-mers on alignment-free genotyping.Semantic proximity Read ↗

Predictive computational phenotyping and biomarker discovery using reference-free genome comparisonsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.