Article
Genome-wide association mapping in bacteria?
Trends in microbiology - 1 Aug 2006
Falush Daniel, Bowden Rory
Abstract excerpt
Bacteria display many interesting phenotypes such as virulence, tissue specificity and host range, for which it would be useful to know the genetic basis. Association mapping involves identifying causal variants by showing that particular genotypes are statistically associated with a phenotypic trait in a sample of strains taken from a natural population. With the advent of high-throughput genotyping, association...
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