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Article

MiR-182 promotes glucose metabolism by upregulating hypoxia-inducible factor 1α in NSCLC cells.

Biochemical and biophysical research communications - 2 Oct 2018

Wang Mingliang, Wang Wendong, Wang Jiashun, Zhang Jun

Abstract excerpt

OBJECTIVE: This study aims to demonstrate the role of miR-182 in the glucose metabolism of NSCLC cells and the potential mechanism. METHODS: MTT Cytotoxicity Assay was used to measure the function of differentially expressed miR-182 on two NSCLC cell lines proliferation. Metabolite analysis was introduced to monitor the glucose consumption, lactate release and glycolytic intermediate metabolites. The mRNA level...

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Identifiers

PMID: 29894685
DOI: 10.1016/j.bbrc.2018.06.035

Genes

ENO1
LDHA
PDK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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