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HK2 and LDHA upregulation mediate hexavalent chromium-induced carcinogenesis, cancer development and prognosis through miR-218 inhibition

24 May 2024

Abstract excerpt

Hexavalent chromium [Cr(VI)] is one of the most common environmental contaminants due to its tremendous industrial applications, but its effects and mechanism remain to be investigated. Our previous studies showed that Cr(VI) exposure caused malignant transformation and tumorigenesis. This study showed that glycolytic proteins HK2 and LDHA levels were statistically significant changed in blood samples of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38795416
DOI: 10.1016/j.ecoenv.2024.116500

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