Article

Loss of MiR-192-5p Initiates a Hyperglycolysis and Stemness Positive Feedback in Hepatocellular Carcinoma.

2020-11-24

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Emerging studies revealed that cancer stem cells (CSCs) possessed peculiar metabolic properties, which however remained largely unknown in hepatocellular carcinoma (HCC). Genetic silencing of liver-abundant miR-192-5p was a key feature for multiple groups of CSC-positive HCCs. We thus aimed to investigate essential metabolic features of hepatic CSCs via using HC...

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Literature Corpus work: f3efe886-fc1a-537c-a4f3-52457f2a8fce
DOI: 10.21203/rs.3.rs-56821/v3

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