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Article

Incidence of inactive allele CYP2D6*4 among Greek women suffering from hormone-sensitive breast cancer.

European journal of gynaecological oncology - 1 Aug 2016

Kykalos S, Mantas D, Charalampoudis P, Kouraklis G, Markopoulos C

Abstract excerpt

BACKGROUND: The incidence of CYP2D6*4 among Caucasians is estimated up to 27%, while it is present in up to 90% of all poor metabolizers within the Caucasian population. The hypothesis under question is whether the presence of one or two non-functioning (null) alleles predicts an inferior outcome in postmenopausal women with breast cancer receiving adjuvant treatment with tamoxifen. The aim of the present study...

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PMID: 29894075

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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