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Article

CYP2D6*4 allele and breast cancer risk: is there any association?

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Feb 2012

Fernández-Santander Ana, del Saz Sánchez Miguel, Tejerina Gómez Armando, Bandrés Moya Fernando

Abstract excerpt

BACKGROUND: CYP2D6 is an important cytochrome P450 enzyme. These enzymes catalyse the oxidative biotransformation of about 25% of clinically important drugs as well as the metabolism of numerous environmental chemical carcinogens. The most frequent null allele of CYP2D6 in European populations, CYP2D6*4, has been studied here in order to elucidate whether a relationship exists between this allele and the risk of...

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Identifiers

PMID: 22301406
DOI: 10.1007/s12094-012-0776-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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