Article
Relationship between the microsatellite D2S388-5 and D2S2232 polymorphisms and chronic obstructive pulmonary disease in the Chinese Kazakh population.
Respirology (Carlton, Vic.) - 1 Feb 2013
Guan Jian, Liu Xian-Sheng, Xu Yong-Jian, Xu Xi-Lin, Yang Yong-Sheng, Wang Ran
Abstract excerpt
BACKGROUND AND OBJECTIVE: Chronic obstructive pulmonary disease (COPD) is influenced by multiple genetic and environmental factors. The role of genetic susceptibility in the pathogenesis of COPD has recently gained more attention. The surface lung surfactant protein B plays an important role in COPD pathogenesis. Microsatellite DNA has been characterized in the surfactant protein B alleles D2S388-5 and D2S2232....
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