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Article

The Role of Mitochondrial Calcium Homeostasis in Alzheimer's and Related Diseases.

International journal of molecular sciences - 1 Dec 2020

Ryan Kerry C, Ashkavand Zahra, Norman Kenneth R

Abstract excerpt

Calcium signaling is essential for neuronal function, and its dysregulation has been implicated across neurodegenerative diseases, including Alzheimer's disease (AD). A close reciprocal relationship exists between calcium signaling and mitochondrial function. Growing evidence in a variety of AD models indicates that calcium dyshomeostasis drastically alters mitochondrial activity which, in turn, drives...

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Identifiers

PMID: 33271784
DOI: 10.3390/ijms21239153
PMCID: PMC7730848

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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