Article
The pathogenesis of Alzheimers disease is it a lifelong "calciumopathy"?
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry - 1 Oct 2007
Stutzmann Grace E
Abstract excerpt
Alzheimer's disease (AD) is a fatal neurodegenerative disorder that has no known cure, nor is there a clear mechanistic understanding of the disease process itself. Although amyloid plaques, neurofibrillary tangles, and cognitive decline are late-stage markers of the disease, it is unclear how they are initially generated, and if they represent a cause, effect, or end phase in the pathology process. Recent...
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