Article
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative.
Microbiome - 8 Jun 2018
Wang Jun, Kurilshikov Alexander, Radjabzadeh Djawad, Turpin Williams, Croitoru Kenneth, Bonder Marc Jan, Jackson Matthew A, Medina-Gomez Carolina, Frost Fabian, Homuth Georg, Rühlemann Malte, Hughes David, Kim Han-Na, Spector Tim D, Bell Jordana T, Steves Claire J, Timpson Nicolas, Franke Andre, Wijmenga Cisca, Meyer Katie, Kacprowski Tim, Franke Lude, Paterson Andrew D, Raes Jeroen, Kraaij Robert, Zhernakova Alexandra
Abstract excerpt
BACKGROUND: In recent years, human microbiota, especially gut microbiota, have emerged as an important yet complex trait influencing human metabolism, immunology, and diseases. Many studies are investigating the forces underlying the observed variation, including the human genetic variants that shape human microbiota. Several preliminary genome-wide association studies (GWAS) have been completed, but more are...
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