Article
Using genetic data to strengthen causal inference in observational research.
Nature reviews. Genetics - 1 Sept 2018
Pingault Jean-Baptiste, O'Reilly Paul F, Schoeler Tabea, Ploubidis George B, Rijsdijk Frühling, Dudbridge Frank
Abstract excerpt
Causal inference is essential across the biomedical, behavioural and social sciences.By progressing from confounded statistical associations to evidence of causal relationships, causal inference can reveal complex pathways underlying traits and diseases and help to prioritize targets for intervention. Recent progress in genetic epidemiology - including statistical innovation, massive genotyped data sets and novel...
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