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Article

Concomitant 1p36 deletion and TNFRSF14 mutations in primary cutaneous follicle center lymphoma frequently expressing high levels of EZH2 protein.

Virchows Archiv : an international journal of pathology - 1 Oct 2018

Gángó Ambrus, Bátai Bence, Varga Martin, Kapczár Dóra, Papp Gergő, Marschalkó Márta, Kuroli Enikő, Schneider Tamás, Csomor Judit, Matolcsy András, Bödör Csaba, Szepesi Ágota

Abstract excerpt

Primary cutaneous follicle center lymphoma (PCFCL) is an indolent variant of follicular lymphoma (FL) with limited information available on the genetic background of the disease. The genetic hallmark of nodal FL, the t(14;18) translocation, affecting the BCL2 gene, is rare in PCFCL. Loss of 1p36, the most common secondary chromosomal abnormality in nodal FL, has been recently reported in 16.7% of PCFCL cases. In...

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Share to Chromosome Deletion
Share to Chromosomes, Human, Pair 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to Enhancer of Zeste Homolog 2 Protein

Share to In Situ Hybridization, Fluorescence

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Share to Proto-Oncogene Proteins c-bcl-2

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Source

Identifiers

PMID: 29858685
DOI: 10.1007/s00428-018-2384-3

Genes

BCL2
TNFRSF14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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