Article
HLA-DQA1, -DQB1, and -DRB1 Alleles Associated with Acute Tubulointerstitial Nephritis in a Chinese Population: A Single-Center Cohort Study.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jul 2018
Jia Yan, Su Tao, Gu Yanghui, Li Cui, Zhou Xujie, Su Jianqun, Sun Pingping, Tang Jiawei, Yang Liu, Liu Gang, Yang Li
Abstract excerpt
Acute tubulointerstitial nephritis (ATIN) is a common cause of acute kidney injury with various origins. HLA-DQA1, -DQB1, and -DRB1 have been associated with development of tubulointerstitial nephritis and uveitis (TINU) syndrome in case reports and small case series, but information about HLA genetic susceptibility to drug hypersensitivity-related ATIN (D-ATIN) or other types of ATIN is limited. In this article,...
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