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Article

Gene expression dynamics following mithramycin treatment: A possible model for post-chemotherapy cognitive impairment.

Clinical and experimental pharmacology & physiology - 1 Oct 2018

Asor Eyal, Ben-Shachar Dorit

Abstract excerpt

Chemotherapy-induced cognitive changes is a major burden on a substantial number of cancer survivors. The mechanism of this sequel is unknown. In this study, we followed long-term effects of early in life mithramycin (MTR) treatment on behaviour and on the normal course of alterations of gene expression in brain. Between post-natal days (PND) 7 and 10, male rats were divided into 2 groups, 1 receiving MTR...

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Source

Identifiers

PMID: 29851136
DOI: 10.1111/1440-1681.12975

Genes

MTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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