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Profiling of gene expression in the brain associated with anxiety-related behaviors in the chronic phase following cranial irradiation

1 Aug 2022

Abstract excerpt

Although the brain is exposed to cranial irradiation in many clinical contexts, including malignant brain tumor therapy, such exposure can cause delayed neuropsychiatric disorders in the chronic phase. However, how specific molecular mechanisms are associated with irradiation-induced behavioral dysfunction, especially anxiety-like behaviors, is unclear. In the present study, we evaluated anxiety-like behaviors in...

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PMID: 35915120
DOI: 10.1038/s41598-022-17310-z

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