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Article

Candidate mechanisms for chemotherapy-induced cognitive changes.

Nature reviews. Cancer - 1 Mar 2007

Ahles Tim A, Saykin Andrew J

Abstract excerpt

The mechanism(s) for chemotherapy-induced cognitive changes are largely unknown; however, several candidate mechanisms have been identified. We suggest that shared genetic risk factors for the development of cancer and cognitive problems, including low-efficiency efflux pumps, deficits in DNA-repair mechanisms and/or a deregulated immune response, coupled with the effect of chemotherapy on these systems, might...

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PMID: 17318212
DOI: 10.1038/nrc2073
PMCID: PMC3329763

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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