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Article

Positive Association between EDN1 rs5370 (Lys198Asn) Polymorphism and Large Artery Stroke in a Ukrainian Population.

Disease markers - 1 Jan 2018

Dubovyk Yevhen I, Oleshko Tetyana B, Harbuzova Viktoriia Yu, Ataman Alexander V

Abstract excerpt

There are a lot of convincing evidences about the involvement of endothelin pathway proteins in the pathogenesis of atherosclerosis and its fatal complications. In this study, the analysis of a possible association between EDN1 rs5370 and EDNRA rs5335 gene polymorphisms and the risk of large artery stroke (LAS) in a Ukrainian population was conducted. 200 LAS patients and 200 unrelated controls were enrolled in a...

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Source

Open in PubMed Open full text

Identifiers

PMID: 29849817
DOI: 10.1155/2018/1695782
PMCID: PMC5903200

Genes

EDN1
EDNRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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