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Article

Association of eNOS and Cav-1 gene polymorphisms with susceptibility risk of large artery atherosclerotic stroke.

PloS one - 1 Jan 2017

Shyu Hann-Yeh, Chen Ming-Hua, Hsieh Yi-Hsien, Shieh Jia-Ching, Yen Ling-Rong, Wang Hsiao-Wei, Cheng Chun-Wen

Abstract excerpt

Endothelial nitric oxide synthase (eNOS) is localized in caveole and has important effects on caveolar coordination through its interaction with caveolin-1 (Cav-1), which supports normal functioning of vascular endothelial cells. However, the relationship between genotypic polymorphisms of e-NOS and Cav-1 genes and ischemic stroke (IS) remains lesser reported. This hospital-based case-control study aimed to...

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Identifiers

PMID: 28346478
DOI: 10.1371/journal.pone.0174110
PMCID: PMC5367681

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