Article
Interaction of angiotensin-converting enzyme and apolipoprotein E gene polymorphisms in ischemic stroke involving large-vessel disease.
Journal of thrombosis and thrombolysis - 1 Jan 2009
Saidi Sarra, Zammiti Walid, Slamia Lamia B, Ammou Sofyan B, Almawi Wassim Y, Mahjoub Touhami
Abstract excerpt
A relationship between apolipoprotein E (Apo E) genotype and angiotensin-converting enzyme (ACE) insertion-deletion (Ins-Del) mutation and stroke was suggested. We investigated the association of Apo E4 and ACE Ins/Del genotypes with stroke risk and changes in serum lipids in 228 consecutive Tunisian stroke patients, and 323 age-and gender-matched controls. Comparable frequencies of ACE Ins/Del alleles were seen...
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