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Article

An Update on Autoinflammatory Diseases: Inflammasomopathies.

Current rheumatology reports - 30 May 2018

Harapas Cassandra R, Steiner Annemarie, Davidson Sophia, Masters Seth L

Abstract excerpt

PURPOSE OF REVIEW: Autoinflammatory diseases are driven by abnormal innate immune activation. In the case of inflammasomopathies, these are all attributable to activation of an inflammasome complex, nucleated by an innate immune sensor such as NLRP3. This review will focus on recent advances that have helped to elucidate the role of three other sensors (NLRP1, NLRC4 and pyrin) which can also cause...

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Source

Identifiers

PMID: 29846819
DOI: 10.1007/s11926-018-0750-4

Genes

NLRC4
NLRP1
NLRP3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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