Article
Autoinflammatory Keratinization Diseases-The Concept, Pathophysiology, and Clinical Implications.
Clinical reviews in allergy & immunology - 1 Dec 2023
Blicharz Leszek, Czuwara Joanna, Rudnicka Lidia, Torrelo Antonio
Abstract excerpt
Recent advances in medical genetics elucidated the background of diseases characterized by superficial dermal and epidermal inflammation with resultant aberrant keratosis. This led to introducing the term autoinflammatory keratinization diseases encompassing entities in which monogenic mutations cause spontaneous activation of the innate immunity and subsequent disruption of the keratinization process....
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