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Article

Hypothetical pathogenesis of age-related macular degeneration and pachychoroid diseases derived from their genetic characteristics.

Japanese journal of ophthalmology - 1 Nov 2020

Yamashiro Kenji, Hosoda Yoshikatsu, Miyake Masahiro, Takahashi Ayako, Ooto Sotaro, Tsujikawa Akitaka

Abstract excerpt

Genetic studies have investigated the pathogenesis of age-related macular degeneration (AMD). The pachychoroid concept has recently garnered attention as a possible explanation for AMD pathogenesis; the genetic characteristics of pachychoroid diseases have also been elucidated. In this review, we summarize previously reported genetic characteristics of AMD and pachychoroid diseases, and analyze these data to...

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PMID: 33006732
DOI: 10.1007/s10384-020-00773-w

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