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Article

Regulation of cancer immune escape: The roles of miRNAs in immune checkpoint proteins.

Cancer letters - 1 Sept 2018

Yang Qin, Cao Wenjie, Wang Zi, Zhang Bin, Liu Jing

Abstract excerpt

Immune checkpoint proteins (ICPs) are regulators of immune system. The ICP dysregulation silences the host immune response to cancer-specific antigens, contributing to the occurrence and progress of various cancers. MiRNAs are regulatory molecules and function in mRNA silencing and post-transcriptional regulation of gene expression. MiRNAs that modulate the immunity via ICPs have received increasing attention....

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PMID: 29800685
DOI: 10.1016/j.canlet.2018.05.015

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