Article
Engineering M13 for phage display.
Biomolecular engineering - 1 Sept 2001
Sidhu S S
Abstract excerpt
Phage display is achieved by fusing polypeptide libraries to phage coat proteins. The resulting phage particles display the polypeptides on their surfaces and they also contain the encoding DNA. Library members with particular functions can be isolated with simple selections and polypeptide sequences can be decoded from the encapsulated DNA. The technology's success depends on the efficiency with which...
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